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(A) Images of the five-inlet <t>microfluidic</t> chip (left) and integrated setup of the microfluidic device with the synchrotron X-ray beam (right). The inlet streams were arranged such that the polymer solution was introduced from the central stream, next to the two angled streams with pure solvent (such as THF) to prevent premature mixing. The antisolvent (water) was introduced via the two orthogonal inlet streams. For measurements of the background scattering, pure THF was introduced from the central stream. (B) Three-dimensional sketch of the configuration and dimensions of the microfluidic device in units of millimeter. All channels were 0.2 mm wide with a standard height of 0.6 mm at the inlet and a stepped-height increase of the orthogonal streams to 1.0 mm. (C) Typical 2D SAXS images captured along the straight channel after subtracting the background solvent scattering. More intense scattering could be observed at the downstream of the channel.
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(A) Images of the five-inlet microfluidic chip (left) and integrated setup of the microfluidic device with the synchrotron X-ray beam (right). The inlet streams were arranged such that the polymer solution was introduced from the central stream, next to the two angled streams with pure solvent (such as THF) to prevent premature mixing. The antisolvent (water) was introduced via the two orthogonal inlet streams. For measurements of the background scattering, pure THF was introduced from the central stream. (B) Three-dimensional sketch of the configuration and dimensions of the microfluidic device in units of millimeter. All channels were 0.2 mm wide with a standard height of 0.6 mm at the inlet and a stepped-height increase of the orthogonal streams to 1.0 mm. (C) Typical 2D SAXS images captured along the straight channel after subtracting the background solvent scattering. More intense scattering could be observed at the downstream of the channel.

Journal: Macromolecules

Article Title: In Situ Measurements of Polymer Micellization Kinetics with Millisecond Temporal Resolution

doi: 10.1021/acs.macromol.8b02257

Figure Lengend Snippet: (A) Images of the five-inlet microfluidic chip (left) and integrated setup of the microfluidic device with the synchrotron X-ray beam (right). The inlet streams were arranged such that the polymer solution was introduced from the central stream, next to the two angled streams with pure solvent (such as THF) to prevent premature mixing. The antisolvent (water) was introduced via the two orthogonal inlet streams. For measurements of the background scattering, pure THF was introduced from the central stream. (B) Three-dimensional sketch of the configuration and dimensions of the microfluidic device in units of millimeter. All channels were 0.2 mm wide with a standard height of 0.6 mm at the inlet and a stepped-height increase of the orthogonal streams to 1.0 mm. (C) Typical 2D SAXS images captured along the straight channel after subtracting the background solvent scattering. More intense scattering could be observed at the downstream of the channel.

Article Snippet: A five-inlet quartz microfluidic chip was custom-fabricated by Translume (Ann Arbor, MI).

Techniques: